


In this rare condition, the adrenal glands don’t work properly and cannot make enough cortisol. Primary AI, also called Addison’s disease.Diseases of overactivity – Cushing’s syndrome, Conn’s syndrome, phaeochromocytomaĪddison's Disease, Adrenal Insufficiency & Adrenal Fatigue What is adrenal insufficiency (AI)?Īdrenal insufficiency (AI) is a condition in which the cortex does not make enough steroid hormones.Diseases of underactivity – Adrenal insufficiency & Addison’s disease.The adrenal medulla normally produces adrenaline (epinephrine) and noradrenaline (norepinephrine) in stressful situations.ĭisorders of adrenal function can be broadly broken down into three groups: The hormone aldosterone, together with the kidneys, regulates the balance of sodium and potassium in the body and plays a major role in maintaining normal blood pressure.

Regulating the metabolism of proteins, carbohydrates, and fats.Suppressing the immune system's inflammatory response.Contributing to maintenance of blood sugar levels, together with insulin.Maintaining blood pressure and cardiovascular function.Cortisol also contributes to other roles including: The inner layer of the gland (medulla) makes adrenaline and noradrenaline, responsible for our ‘fight or flight’ response.Ĭortisol is one of the body’s most important hormones its principal role is to help the body respond to stress. The outer layer (cortex) of the adrenal glands makes three types of steroid hormones: (i) aldosterone, which is required for salt and water balance, (ii) cortisol required as our body’s main stress hormone, and (iii) androgens (male hormones). The adrenal glands make hormones that are essential for body functions. The gland consists of an outer part (cortex) and inner part (medulla). They are normally small golden-yellow triangle shaped glands located on top of each kidney. The adrenal glands are endocrine organs that secrete hormones directly into the bloodstream. Adrenal Diseases What are adrenal glands?
